For which of the following diseases is treatment typically not straightforward due to high toxicity?

Viral hepatitis represents a condition where treatment can often be complex due to the potential for high toxicity associated with its therapies. Specifically, certain antiviral medications used to manage viral hepatitis can have significant side effects and require careful monitoring to mitigate risks. This contrasts with the other conditions listed.

For example, the common cold and flu are typically managed with supportive care and over-the-counter medications that are less likely to produce severe toxicity. Strep throat, which is a bacterial infection, is generally treated with widely used antibiotics that are effective and have a well-established safety profile. In contrast, the treatment protocols for viral hepatitis may involve medications that can affect liver function or have other serious side effects, making the management of this disease distinctly more complicated and necessitating a more cautious approach.